Oral Anticoagulants

Warfarin and related drugs have been used for over half a century in prevention and treatment of thrombotic disorders. Only recently however has their clinical role been firmly established by randomized studies and their benefit/risk ratio improved by lower dosetherapy with improvements in laboratory monitoring. An international team of recognized experts provide detailed coverage on the mode of action; clinical pharmacodynamics; magnitude and sources of variability in individuals response to oral anticoagulant; methods of individualizing dosing regimens; laboratory monitoring; and comparison between the different currently prescribed oral anticoagulants. This is a detailed and comprehensive treatise on oral anticoagulants and their clinical application...a very comprehensive book.Journal of Human Hypertension